CYP3A4 inducers may well raise the development of the neurotoxic/nephrotoxic ifosfamide metabolite, chloroacetaldehyde. Intently observe clients taking ifosfamide with CYP3A4 inducers for toxicities and consider dose adjustment.Reserve concomitant prescribing of those drugs in sufferers for whom other treatment solutions are inadequate. Limit dosag